Invention Grant
- Patent Title: Modulation of HIF1-beta expression
- Patent Title (中): 调节HIF1-β表达
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Application No.: US12578468Application Date: 2009-10-13
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Publication No.: US07799764B2Publication Date: 2010-09-21
- Inventor: Eric G. Marcusson , Scott W. Henry , Youngsoo Kim , Kenneth Dobie
- Applicant: Eric G. Marcusson , Scott W. Henry , Youngsoo Kim , Kenneth Dobie
- Applicant Address: US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Knobbe Martens Olson & Bear LLP
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/02 ; C07H21/04 ; C12Q1/68 ; C12N5/00
Abstract:
Compounds, compositions and methods are provided for modulating the expression of HIF1-beta. The compositions comprise oligonucleotides, targeted to nucleic acid encoding HIF1-beta. Methods of using these compounds for modulation of HIF1-beta expression and for diagnosis and treatment of diseases and conditions associated with expression of HIF1-beta are provided.
Public/Granted literature
- US20100113573A1 MODULATION OF HIF1 BETA EXPRESSION Public/Granted day:2010-05-06
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