Invention Grant
- Patent Title: Quinoxaline derivatives of alpha-2 adrenergic agonists
- Patent Title (中): α-2肾上腺素能激动剂的喹喔啉衍生物
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Application No.: US12162529Application Date: 2007-02-02
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Publication No.: US07799784B2Publication Date: 2010-09-21
- Inventor: Francesca Benedini , Francesco Impagnatiello , Stefano Biondi , Ennio Ongini , Wesley Kwan Mung Chong
- Applicant: Francesca Benedini , Francesco Impagnatiello , Stefano Biondi , Ennio Ongini , Wesley Kwan Mung Chong
- Applicant Address: FR Sophia Antipolis-Valbonne
- Assignee: Nicox S.A.
- Current Assignee: Nicox S.A.
- Current Assignee Address: FR Sophia Antipolis-Valbonne
- Agency: Arent Fox LLP
- International Application: PCT/EP2007/051017 WO 20070202
- International Announcement: WO2007/090793 WO 20070816
- Main IPC: A61K31/495
- IPC: A61K31/495
Abstract:
The present invention relates to alpha2-adrenergic receptor agonist nitrooxyderivatives, including the following structure, having improved pharmacological activity and enhanced tolerability. They can be employed for the treatment of ocular diseases, in particular high intraocular pressure and glaucoma.
Public/Granted literature
- US20080318965A1 Derivatives of Alpha2-Adrenergic Receptor Agonist Public/Granted day:2008-12-25
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