Invention Grant
- Patent Title: Spiroheterocyclic compounds and their uses as therapeutic agents
- Patent Title (中): 螺杂环化合物及其作为治疗剂的用途
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Application No.: US11402200Application Date: 2006-04-11
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Publication No.: US07799798B2Publication Date: 2010-09-21
- Inventor: Mikhail Chafeev , Sultan Chowdhury , Robert Fraser , Jianmin Fu , Rajender Kamboj , Shifeng Liu , Mehran Seid Bagherzadeh , Jianyu Sun , Serguei Sviridov
- Applicant: Mikhail Chafeev , Sultan Chowdhury , Robert Fraser , Jianmin Fu , Rajender Kamboj , Shifeng Liu , Mehran Seid Bagherzadeh , Jianyu Sun , Serguei Sviridov
- Applicant Address: CA Burnaby
- Assignee: Xenon Pharmaceuticals Inc.
- Current Assignee: Xenon Pharmaceuticals Inc.
- Current Assignee Address: CA Burnaby
- Agency: Seed IP Law Group PLLC
- Agent Thong N. Trinh
- Main IPC: A61K31/437
- IPC: A61K31/437 ; C07D491/22

Abstract:
This invention is directed to spiroheterocyclic compounds of formula (I) wherein k, j, p, Q, R1, R3a, R3b, R3c, and R3d are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, that are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. Pharmaceutical compositions comprising the compounds and methods of using the compounds are also disclosed.
Public/Granted literature
- US20060252758A1 Spiroheterocyclic compounds and their uses as therapeutic agents Public/Granted day:2006-11-09
Information query
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