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US07799798B2 Spiroheterocyclic compounds and their uses as therapeutic agents 失效
螺杂环化合物及其作为治疗剂的用途

Spiroheterocyclic compounds and their uses as therapeutic agents
Abstract:
This invention is directed to spiroheterocyclic compounds of formula (I) wherein k, j, p, Q, R1, R3a, R3b, R3c, and R3d are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, that are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. Pharmaceutical compositions comprising the compounds and methods of using the compounds are also disclosed.
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