Invention Grant
US07799806B2 Substituted n-benzyl piperidines as somatostatin receptor modulators
失效
取代的正丁基哌啶作为生长抑素受体调节剂
- Patent Title: Substituted n-benzyl piperidines as somatostatin receptor modulators
- Patent Title (中): 取代的正丁基哌啶作为生长抑素受体调节剂
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Application No.: US12053781Application Date: 2008-03-24
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Publication No.: US07799806B2Publication Date: 2010-09-21
- Inventor: Konrad Bleicher , Andreas D. Christ , Rainer E. Martin , Peter Mohr
- Applicant: Konrad Bleicher , Andreas D. Christ , Rainer E. Martin , Peter Mohr
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Dennis P. Tramaloni; Samuel H. Megerditchian
- Priority: EP07105617 20070404
- Main IPC: A61K31/445
- IPC: A61K31/445

Abstract:
This invention relates to compounds of the formula wherein A, R1 to R3 are as defined in the claims and G is benzoimidazole, quinoxaline, benzotriazole, dihydro-imidazo[4,5-c]pyridinone and dihydro-isoindolone group as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5 such as diabetes mellitus.
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