Invention Grant
- Patent Title: Methods and compositions for increasing the efficiency of therapeutic antibodies using NK cell potentiating compounds
- Patent Title (中): 使用NK细胞增强化合物提高治疗性抗体效率的方法和组合物
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Application No.: US10897624Application Date: 2004-07-23
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Publication No.: US07803376B2Publication Date: 2010-09-28
- Inventor: Andrea Velardi , Francois Romagne
- Applicant: Andrea Velardi , Francois Romagne
- Applicant Address: FR Marseilles
- Assignee: Innate Pharma S.A.
- Current Assignee: Innate Pharma S.A.
- Current Assignee Address: FR Marseilles
- Agency: Saliwanchik, Lloyd & Saliwanchik
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
The present invention relates, generally, to methods and compositions for increasing the efficiency of therapeutic antibodies. Their efficiency is enhanced through the increase of the ADCC mechanism. More particularly, the invention relates to the use of a therapeutic antibody in combination with compounds that block an inhibitory receptor or stimulate an activating receptor of an NK cell in order to enhance the efficiency of the treatment with therapeutic antibodies in human subjects.
Public/Granted literature
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