Invention Grant
US07803386B2 Poly-gamma-glutamic conjugates for eliciting immune responses directed against bacilli
有权
用于引发针对杆菌的免疫应答的聚-γ-谷氨酸缀合物
- Patent Title: Poly-gamma-glutamic conjugates for eliciting immune responses directed against bacilli
- Patent Title (中): 用于引发针对杆菌的免疫应答的聚-γ-谷氨酸缀合物
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Application No.: US10559825Application Date: 2004-06-04
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Publication No.: US07803386B2Publication Date: 2010-09-28
- Inventor: Rachel Schneerson , Stephen Leppla , John B. Robbins , Joseph Shiloach , Joanna Kubler-Kielb , Darrell Liu , Fathy Majadly
- Applicant: Rachel Schneerson , Stephen Leppla , John B. Robbins , Joseph Shiloach , Joanna Kubler-Kielb , Darrell Liu , Fathy Majadly
- Applicant Address: US DC Washington
- Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
- Current Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/US2004/017736 WO 20040604
- International Announcement: WO2005/000884 WO 20050106
- Main IPC: A61K39/02
- IPC: A61K39/02 ; A61K49/00 ; A61K39/07
Abstract:
Immunogenic compositions and methods for eliciting an immune response against B. anthracis and other bacilli are provided that include immunogenic conjugates of a poly-γ-glutamic acid (γPGA) polypeptide of B. anthracis, or of another Bacillus that expresses a γPGA polypeptide. The γPGA conjugates elicit an effective immune response against B. anthracis, or against another Bacillus, in mammalian hosts to which the conjugates are administered.
Public/Granted literature
- US20060134143A1 Poly-gamma-glutamic conjugates for eliciting immune responses directed against bacilli Public/Granted day:2006-06-22
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