Invention Grant
- Patent Title: Chlamydia PMP proteins, gene sequences and uses thereof
- Patent Title (中): 衣原体PMP蛋白，基因序列及其用途
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Application No.: US11781203Application Date: 2007-07-20
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Publication No.: US07803388B2Publication Date: 2010-09-28
- Inventor: W. James Jackson
- Applicant: W. James Jackson
- Applicant Address: US MD Gaithersburg
- Assignee: Emergent Product Development Gaithersburg, Inc.
- Current Assignee: Emergent Product Development Gaithersburg, Inc.
- Current Assignee Address: US MD Gaithersburg
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: A61K39/118
- IPC: A61K39/118 ; A61K39/38 ; A61K39/02 ; A61K39/00 ; A61K38/00
Abstract:
The invention discloses the Chlamydia PMPE and PMPI polypeptide, polypeptides derived therefrom, (PMP-derived polypeptides), nucleotide sequences encoding said polypeptides, antibodies that specifically bind the PMP polypeptides and PMP-derived polypeptides and T-cells specific for PMP polypeptides and PMP-derived polypeptides. Also disclosed are prophylactic and therapeutic compositions, including immunogenic compositions, e.g., vaccines, comprising PMP polypeptides or PMP-derived polypeptides or antibodies thereto. The invention additionally discloses methods of inducing in animals an immune response to Chlamydia cells, Chlamydia elementary bodies, and/or cells expressing Chlamydial proteins, e.g., cell infected with Chlamydia.
Public/Granted literature
- US20070292425A1 Chlamydia PMP Proteins, Gene Sequences and Uses Thereof Public/Granted day:2007-12-20
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