Invention Grant
US07803411B2 Physiologically active substance NK13650P3, method of producing the same and use thereof
失效
生理活性物质NK13650P3,其生产方法及其应用
- Patent Title: Physiologically active substance NK13650P3, method of producing the same and use thereof
- Patent Title (中): 生理活性物质NK13650P3,其生产方法及其应用
-
Application No.: US11922266Application Date: 2006-06-26
-
Publication No.: US07803411B2Publication Date: 2010-09-28
- Inventor: Arihiro Tomura , Junko Odanaka , Masakazu Nishimoto
- Applicant: Arihiro Tomura , Junko Odanaka , Masakazu Nishimoto
- Applicant Address: JP Tokyo
- Assignee: Nippon Kayaku Kabushiki Kaisha
- Current Assignee: Nippon Kayaku Kabushiki Kaisha
- Current Assignee Address: JP Tokyo
- Agency: Nields, Lemack & Frame, LLC
- Priority: JP2005-186182 20050627
- International Application: PCT/JP2006/312726 WO 20060626
- International Announcement: WO2007/000978 WO 20070104
- Main IPC: A61K35/00
- IPC: A61K35/00 ; A01N65/04 ; C12P1/02

Abstract:
A physiologically active substance NK13650P3 having the following physicochemical properties or a pharmacologically acceptable salt thereof. 1) Appearance: pale yellow powder 2) Molecular formula: C29H37N7O15 3) Molecular weight: 723 4) Hydrogen nuclear magnetic resonance spectrum: spectrum measured at 600 MHz in heavy water contains the following signals: chemical shift value δ ppm: 7.05 (1H, 3), 7.00 (1H, d), 6.96 (1H, d), 6.83 (1H, s), etc. 5) Carbon nuclear magnetic resonance spectrum: spectrum measured at 150 MHz in heavy water contains the following signals: chemical shift value δ ppm: 181.5(s), 181.4(s), 179.9(s), 179.2(s), 174.5(s), 174.3(s), 171.5(s), 165.4(s), etc. 6) Ultraviolet light spectrum: spectrum measured in aqueous solution contains the following UV absorption bands: λmax (MeOH): 196.5 nm, 224.5 nm, 322.5 nm 7) Solubility: highly soluble in water but insoluble in methanol, acetone, ethyl acetate, chloroform and dimethyl sulfoxide. 8) Coloration reaction: positive to phosphomolybdic acid/sulfuric acid reaction and Rydon-Smith reaction.
Public/Granted literature
- US20090041799A1 Physiologically Active Substance NK13650P3, Method of Producing the Same and Use Thereof Public/Granted day:2009-02-12
Information query