Invention Grant
US07803522B2 Elastin producing fibroblast formulations and methods of using the same
有权
弹性蛋白生成成纤维细胞配方及其使用方法
- Patent Title: Elastin producing fibroblast formulations and methods of using the same
- Patent Title (中): 弹性蛋白生成成纤维细胞配方及其使用方法
-
Application No.: US11435563Application Date: 2006-05-17
-
Publication No.: US07803522B2Publication Date: 2010-09-28
- Inventor: Felipe Jimenez , Thomas Mitts , Aleksander Hinek
- Applicant: Felipe Jimenez , Thomas Mitts , Aleksander Hinek
- Applicant Address: US CA Visalia CA Toronto, Ontario
- Assignee: Human Matrix Sciences, LLC,The Hospital for Sick Children
- Current Assignee: Human Matrix Sciences, LLC,The Hospital for Sick Children
- Current Assignee Address: US CA Visalia CA Toronto, Ontario
- Agency: Pepper Hamilton LLP
- Main IPC: A01N1/00
- IPC: A01N1/00 ; C12N5/00
Abstract:
The present invention describes therapeutic compositions comprising fibroblasts that have been stimulated to increase expression of extracellular matrix components or elastin, or to produce enhanced elastogenesis or the appearance thereof at a site of administration. The therapeutic fibroblast formulations can be prepared using a variety of elastogenic agents, including digests of mammalian elastin, chemically digested plant extracts comprising elastin-like peptides, and synthetic elastogenic peptides. The invention further comprises cosmetic and pharmaceutical treatment methods using the therapeutic fibroblast compositions of the invention.
Public/Granted literature
- US20080050346A1 Elastin producing fibroblast formulations and methods of using the same Public/Granted day:2008-02-28
Information query
