Invention Grant
- Patent Title: Methods of screening for antagonists of mammalian monocyte chemoattractant protein receptors
- Patent Title (中): 筛选哺乳动物单核细胞趋化蛋白受体拮抗剂的方法
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Application No.: US11702711Application Date: 2007-02-05
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Publication No.: US07803560B2Publication Date: 2010-09-28
- Inventor: Israel F. Charo , Shaun R. Coughlin
- Applicant: Israel F. Charo , Shaun R. Coughlin
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Townsend and Townsend and Crew LLP
- Main IPC: G01N33/566
- IPC: G01N33/566 ; G01N33/58 ; G01N33/68
Abstract:
Novel human chemokine receptors, MCP-1RA and MCP-1RB, and processes for producing them are disclosed. The receptors, which are alternately spliced versions of MCP-1 receptor protein may be used in an assay to identify antagonists of MCP-1 which are therapeutically useful in the treatment of atherosclerosis and other diseases characterized by monocytic infiltrates.
Public/Granted literature
- US20090123938A1 Mammalian monocyte chemoattractant protein receptors Public/Granted day:2009-05-14
Information query
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