Invention Grant
- Patent Title: Use of lymphocytes to measure anthrax lethal toxin activity
- Patent Title (中): 使用淋巴细胞测量炭疽致死毒素活性
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Application No.: US11399003Application Date: 2006-04-05
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Publication No.: US07803565B1Publication Date: 2010-09-28
- Inventor: David M. Frucht , Hui Fang
- Applicant: David M. Frucht , Hui Fang
- Applicant Address: US DC Washington
- Assignee: The United States of America as represented by the Department of Health and Human Services
- Current Assignee: The United States of America as represented by the Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Klarquist Sparkman, LLP
- Main IPC: G01N33/00
- IPC: G01N33/00 ; G01N33/53 ; G01N33/569 ; G01N33/573 ; C12N5/07 ; C12N5/16
Abstract:
It is disclosed herein that isolated lymphocytes, such as human B-cells and CD4+ T-cell can be used to determine an amount of lymphocyte-associated anthrax lethal toxin activity present. Methods of using isolated lymphocytes to identify anthrax therapeutic agents and to determine the efficacy of a potential anthrax therapeutic are disclosed. Methods are also provided for diagnosing and treating anthrax infections.
Public/Granted literature
- US20100227349A1 USE OF LYMPHOCYTES TO MEASURE ANTHRAX LETHAL TOXIN ACTIVITY Public/Granted day:2010-09-09
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