Invention Grant
US07803569B2 Marburg I mutant of factor VII activating protease (FSAP) as risk factor for arterial thrombosis and methods of detecting FSAP and FSAP mutations
有权
因子VII激活蛋白酶（FSAP）的Marburg I突变体作为动脉血栓形成的危险因素，以及检测FSAP和FSAP突变的方法
- Patent Title: Marburg I mutant of factor VII activating protease (FSAP) as risk factor for arterial thrombosis and methods of detecting FSAP and FSAP mutations
- Patent Title (中): 因子VII激活蛋白酶（FSAP）的Marburg I突变体作为动脉血栓形成的危险因素，以及检测FSAP和FSAP突变的方法
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Application No.: US11633501Application Date: 2006-12-05
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Publication No.: US07803569B2Publication Date: 2010-09-28
- Inventor: Stefan Kiechl , Johann Willeit , Christian Josef Wiedermann , Juergen Roemisch , Thomas Weimer , Annette Feussner , Hans-Arnold Stoehr , Volker Doersam , Wiegand Lang , Margret Becker , Claudia Nerlich , Gudrun Muth-Naumann , Bernd Knoblauch
- Applicant: Stefan Kiechl , Johann Willeit , Christian Josef Wiedermann , Juergen Roemisch , Thomas Weimer , Annette Feussner , Hans-Arnold Stoehr , Volker Doersam , Wiegand Lang , Margret Becker , Claudia Nerlich , Gudrun Muth-Naumann , Bernd Knoblauch
- Applicant Address: DE Marburg
- Assignee: CSL Behring GmbH
- Current Assignee: CSL Behring GmbH
- Current Assignee Address: DE Marburg
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Priority: DE10036641 20000726; DE10050040 20001010; DE10052319 20001021; DE10118706 20010412; DE10212246 20020319; DE10238429 20020816
- Main IPC: C12Q1/56
- IPC: C12Q1/56 ; C12Q1/68 ; C12Q1/37 ; G01N33/53 ; G01N33/00 ; C12N9/48 ; C07H21/04
Abstract:
An arterial thrombosis risk factor comprising one or more of the identified mutants of coagulation factor VII activating protease (FSAP) is described. In addition, diagnostic determination methods for detecting these mutants which are identified as risk factors are described.
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