Invention Grant
US07803630B2 Method for detecting target compounds containing sulfenic acids using new reagents
有权
使用新试剂检测含有亚磺酸的目标化合物的方法
- Patent Title: Method for detecting target compounds containing sulfenic acids using new reagents
- Patent Title (中): 使用新试剂检测含有亚磺酸的目标化合物的方法
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Application No.: US11863413Application Date: 2007-09-28
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Publication No.: US07803630B2Publication Date: 2010-09-28
- Inventor: Leslie B. Poole , S. Bruce King , Jacquelyn S. Fetrow
- Applicant: Leslie B. Poole , S. Bruce King , Jacquelyn S. Fetrow
- Applicant Address: US NC Winston-Salem
- Assignee: Wake Forest University Health Sciences
- Current Assignee: Wake Forest University Health Sciences
- Current Assignee Address: US NC Winston-Salem
- Agency: Myers Bigel Sibley & Sajovec, P.A.
- Main IPC: G01N33/48
- IPC: G01N33/48
Abstract:
The present invention provides compounds of Formula I: wherein: R1 is a label (e.g., a detectable groups; an anti-tumor agent)s; L is present or absent and when present is a linking group; and x represents an integer from 1 to 10; or a pharmaceutically acceptable salt thereof. the compounds are useful for, among other things, identifying cysteine sulfenic acids in proteins and monitoring oxidative damage in proteins and cells.
Public/Granted literature
- US20080070261A1 SULFENIC ACID-REACTIVE COMPOUNDS Public/Granted day:2008-03-20
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