Invention Grant
- Patent Title: Substrates and assays for β-secretase
- Patent Title (中): 底物和分析仪
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Application No.: US10801487Application Date: 2004-03-16
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Publication No.: US07803739B2Publication Date: 2010-09-28
- Inventor: Riqiang Yan , Alfredo G. Tomasselli , Mark E. Gurney , Thomas L. Emmons , Michael Jerome Bienkowski , Robert L. Heinrikson
- Applicant: Riqiang Yan , Alfredo G. Tomasselli , Mark E. Gurney , Thomas L. Emmons , Michael Jerome Bienkowski , Robert L. Heinrikson
- Applicant Address: US CA South San Francisco
- Assignee: Elan Pharmaceuticals, Inc.
- Current Assignee: Elan Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: C40B30/00
- IPC: C40B30/00
Abstract:
The present invention is directed to novel substrates for Hu-Asp. More particularly, the invention provides peptide substrates and fusion polypeptide substrates comprising a β-secretase cleavage site. Methods and compositions for making and using the peptides are disclosed.
Public/Granted literature
- US20040241792A1 Substrates and assays for beta-secretase Public/Granted day:2004-12-02
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