Invention Grant
US07803766B2 Gastrin compositions and formulations, and methods of use and preparation 失效
胃泌素组合物和制剂,以及使用和制备方法

Gastrin compositions and formulations, and methods of use and preparation
Abstract:
The present invention concerns six novel variants of alternative splicing of the CD40 receptorThe invention provides a pharmaceutical composition comprising a gastrin compound having an extended activity upon administration to a subject in comparison with native gastrin. Methods are provided of conjugating portions of the amino acid sequence of gastrin having functional ability to bind to the gastrin/CCK receptor, to various carrier moieties, including the use of amino acid spacer regions, and use of bifunctional cross-linking reagents. Methods of treating a diabetes patient with the compositions are provided.
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