Invention Grant
- Patent Title: Heterocyclic derived metalloprotease inhibitors
- Patent Title (中): 杂环衍生金属蛋白酶抑制剂
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Application No.: US11858972Application Date: 2007-09-21
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Publication No.: US07803793B2Publication Date: 2010-09-28
- Inventor: Yue-Mei Zhang , Bangping Xiang , Shyh-Ming Yang , Kenneth Rhodes , Robert Scannevin , Paul Jackson , Davraj Chakravarty , Xiaodong Fan , Lawrence J. Wilson , Prabha Karnachi
- Applicant: Yue-Mei Zhang , Bangping Xiang , Shyh-Ming Yang , Kenneth Rhodes , Robert Scannevin , Paul Jackson , Davraj Chakravarty , Xiaodong Fan , Lawrence J. Wilson , Prabha Karnachi
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE
- Main IPC: C07D225/02
- IPC: C07D225/02 ; C07D401/06 ; C07D401/12 ; C07D409/12 ; A61K31/55
Abstract:
This invention provides novel heterocyclic derived matrix metalloprotease inhibitors of the formula: and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing matrix metalloproteases. This invention also provides therapeutic and prophylactic methods using the instant pharmaceutical compositions.
Public/Granted literature
- US20080103129A1 HETEROCYCLIC DERIVED METALLOPROTEASE INHIBITORS Public/Granted day:2008-05-01
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