Invention Grant
- Patent Title: Indol-3-yl-corbonyl-piperidin-benzoimidazol derivatives
- Patent Title (中): 吲哚-3-基 - 羰基 - 哌啶 - 苯并咪唑衍生物
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Application No.: US11490305Application Date: 2006-07-20
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Publication No.: US07803815B2Publication Date: 2010-09-28
- Inventor: Caterina Bissantz , Christophe Grundschober , Hasane Ratni , Mark Rogers-Evans , Patrick Schnider
- Applicant: Caterina Bissantz , Christophe Grundschober , Hasane Ratni , Mark Rogers-Evans , Patrick Schnider
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- Priority: EP05106695 20050721; EP05110506 20051109
- Main IPC: A61K31/454
- IPC: A61K31/454 ; C07D403/14
Abstract:
The present invention relates to Indol-3-yl-carbonyl-piperidin-benzoimidazol derivatives which act as V1a receptor antagonists and which are represented by Formula I: wherein the residues R1 to R7 are as defined herein. The invention further relates to pharmaceutical compositions containing such compounds, their use in treating dysmenorrhea, hypertension, chronic heart failure, inappropriate secretion of vasopressin, liver cirrhosis, nephritic syndrome, obsessive compulsive disorder, anxiety and depressive disorders, and methods of preparation thereof.
Public/Granted literature
- US20070021463A1 Indol-3-yl-carbonyl-piperidin-benzoimidazol derivatives Public/Granted day:2007-01-25
Information query
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