Invention Grant
- Patent Title: Antibodies against IL-13 receptor alpha1 and uses thereof
- Patent Title (中): 针对IL-13受体α1的抗体及其用途
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Application No.: US11325197Application Date: 2006-01-03
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Publication No.: US07807158B2Publication Date: 2010-10-05
- Inventor: Josef Endl , Maria Elena Fuentes , Yvo Graus , Adelbert Grossmann , Sebastian Neumann , Paul Parren , Frank Rebers , Joerg Thomas Regula , Ralf Schumacher , Stefan Seeber , Jan Olaf Stracke , Kay-Gunnar Stubenrauch , Jan Van De Winkel , Martine Van Vugt , Sandra Vereecken-Verploegen
- Applicant: Josef Endl , Maria Elena Fuentes , Yvo Graus , Adelbert Grossmann , Sebastian Neumann , Paul Parren , Frank Rebers , Joerg Thomas Regula , Ralf Schumacher , Stefan Seeber , Jan Olaf Stracke , Kay-Gunnar Stubenrauch , Jan Van De Winkel , Martine Van Vugt , Sandra Vereecken-Verploegen
- Applicant Address: US CA Palo Alto
- Assignee: Roche Palo Alto LLC
- Current Assignee: Roche Palo Alto LLC
- Current Assignee Address: US CA Palo Alto
- Agent Grant D. Green
- Priority: EP05000003 20050103; EP05002229 20050203
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
The instant specification discloses an antibody binding to IL-13Rα1, inhibiting IL-13 bioactivity and comprising a variable heavy and a variable light chain, characterized in that the variable heavy chain amino acid sequence CDR3 of this antibody is selected from the group consisting of the heavy chain CDR3 sequences of SEQ ID NO: 1, 3, 5, 7 or 9, and this antibody is useful in the treatment of asthma and allergic diseases.
Public/Granted literature
- US20060263356A1 Antibodies against IL-13 receptor alpha1 and uses thereof Public/Granted day:2006-11-23
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