Invention Grant
- Patent Title: Humanized anti-human osteopontin antibody
- Patent Title (中): 人源化抗人骨桥蛋白抗体
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Application No.: US11755671Application Date: 2007-05-30
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Publication No.: US07807161B2Publication Date: 2010-10-05
- Inventor: Nobuchika Yamamoto , Fumihiko Sakai , Hirofumi Higuchi , Masaharu Torikai , Toshihiro Nakashima
- Applicant: Nobuchika Yamamoto , Fumihiko Sakai , Hirofumi Higuchi , Masaharu Torikai , Toshihiro Nakashima
- Applicant Address: JP Tokyo JP Kumamoto-shi
- Assignee: Astellas Pharma Inc.,Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
- Current Assignee: Astellas Pharma Inc.,Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
- Current Assignee Address: JP Tokyo JP Kumamoto-shi
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2006-152892 20060531
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/395 ; C07K16/46 ; C07K16/24
Abstract:
The present invention provides a humanized anti-human osteopontin antibody having better activities (antigen binding activity, leukocyte migration inhibitory activity and the like) and/or stability (resistance to heat, low-pH conditions, denaturants and the like) than those of conventional anti-human osteopontin antibodies.
Public/Granted literature
- US20090053212A1 HUMANIZED ANTI-HUMAN OSTEOPONTIN ANTIBODY Public/Granted day:2009-02-26
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