Invention Grant
US07807171B2 Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
有权
针对P-糖蛋白170的治疗性疫苗用于抑制癌症治疗中的多药耐药性
- Patent Title: Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
- Patent Title (中): 针对P-糖蛋白170的治疗性疫苗用于抑制癌症治疗中的多药耐药性
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Application No.: US10902276Application Date: 2004-07-30
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Publication No.: US07807171B2Publication Date: 2010-10-05
- Inventor: Pierre-Francois Tosi , Claudie Madoulet , Claude Nicolau , David T. Hickman
- Applicant: Pierre-Francois Tosi , Claudie Madoulet , Claude Nicolau , David T. Hickman
- Applicant Address: CH Lausanne
- Assignee: AC Immune SA
- Current Assignee: AC Immune SA
- Current Assignee Address: CH Lausanne
- Agency: Pequignot + Myers LLC
- Agent Joyce von Natzmer
- Priority: FR0309188 20030725
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
The invention relates to an immunogenic composition which comprises, firstly, a carrier and, secondly, as antigenic structure, conjugates comprising all or part of the amino acid sequences of at least one peptide derived from an extracellular loop of the P-170 protein, each peptide being combined with several molecules of fatty acid containing a carbon chain of between C12 and C24 so as to allow, under suitable administration conditions, the induction of anti-P-170 antibodies.The invention relates to said composition for defining means for treating multidrug resistances.
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