Invention Grant
- Patent Title: Segment of glycosylation-deficient HGFalpha-chain
- Patent Title (中): 糖基化缺陷型HGFalpha链的区段
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Application No.: US10926088Application Date: 2004-08-26
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Publication No.: US07807177B2Publication Date: 2010-10-05
- Inventor: Toshikazu Nakamura , Kunio Matsumoto , Kazuhiro Fukuta
- Applicant: Toshikazu Nakamura , Kunio Matsumoto , Kazuhiro Fukuta
- Applicant Address: JP Kyoto JP Osaka
- Assignee: Toshikazu Nakamura,Kringle Pharma Inc.
- Current Assignee: Toshikazu Nakamura,Kringle Pharma Inc.
- Current Assignee Address: JP Kyoto JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2004-018882 20040127
- Main IPC: C07K14/575
- IPC: C07K14/575 ; A61K38/22 ; C12N15/00
Abstract:
The present invention provides a segment of glycosylation-deficient HGF having mutation(s) introduced into an amino acid sequence so as to prevent glycosylation at at least one glycosylation site of a hepatocyte growth factor (HGF), and a method of producing the same. The segment of glycosylation-deficient HGF of the present invention has the same activity as that of a segment of glycosylated HGF, therefore, it is useful as an alternate for a segment of glycosylated HGF.
Public/Granted literature
- US20050164918A1 Segment of glycosylation-deficient HGFalpha-chain Public/Granted day:2005-07-28
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