Invention Grant
US07807178B2 Muteins of placental growth factor type I, preparation method and application thereof
有权
胎盘生长因子I型的突变蛋白，其制备方法和应用
- Patent Title: Muteins of placental growth factor type I, preparation method and application thereof
- Patent Title (中): 胎盘生长因子I型的突变蛋白，其制备方法和应用
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Application No.: US11967469Application Date: 2007-12-31
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Publication No.: US07807178B2Publication Date: 2010-10-05
- Inventor: Giuseppe Salvia
- Applicant: Giuseppe Salvia
- Applicant Address: IT Catania
- Assignee: Geymonat S.p.A.
- Current Assignee: Geymonat S.p.A.
- Current Assignee Address: IT Catania
- Agency: Beusse Wolter Sanks Mora & Maire
- Agent Timothy H. Van Dyke
- Priority: ITRM2002A0277 20020517
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/18 ; C07K14/00
Abstract:
The present invention relates to chemically stable muteins of type 1 Placental Growth Factor (PLGF-1) bearing the substitution or elimination of a cysteine residue from the wild type protein amino acid sequence, their preparation, their therapeutic and cosmetic uses, and pharmaceutical and cosmetic compositions containing the derivatives. The invention likewise relates to the production of antibodies for the derivatives and their use in the diagnosis and treatment of tumoral and non-tumoral pathologies.
Public/Granted literature
- US20090082268A1 Muteins of Placental Growth Factor Type I, Preparation Method And Application Thereof Public/Granted day:2009-03-26
Information query
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