Invention Grant
- Patent Title: Cleavage of nucleic acids
- Patent Title (中): 切断核酸
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Application No.: US11708623Application Date: 2007-02-16
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Publication No.: US07807365B2Publication Date: 2010-10-05
- Inventor: Joseph A. Sorge
- Applicant: Joseph A. Sorge
- Applicant Address: US MA Marlborough
- Assignee: Hologic, Inc.
- Current Assignee: Hologic, Inc.
- Current Assignee Address: US MA Marlborough
- Agent Theodore Allen; Paul Nuzzi
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/02 ; C07H21/04
Abstract:
The invention relates to compositions and methods of generating a signal indicative of the presence of a target nucleic acid in a sample, where the method includes forming a cleavage structure by incubating a sample comprising a target nucleic acid with a probe. The invention also includes the steps of cleaving the cleavage structure with a nuclease to release a nucleic acid fragment to generate a signal, wherein generation of the signal is indicative of the presence of a target nucleic acid in a sample.
Public/Granted literature
- US20070212725A1 Cleavage of nucleic acids Public/Granted day:2007-09-13
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