Invention Grant
- Patent Title: Peptides for discrimination of prions
- Patent Title (中): 用于歧视朊病毒的肽
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Application No.: US12357888Application Date: 2009-01-22
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Publication No.: US07807386B2Publication Date: 2010-10-05
- Inventor: Jian Zheng
- Applicant: Jian Zheng
- Applicant Address: US NJ Raritan
- Assignee: Ortho-Clinical Diagnostics, Inc.
- Current Assignee: Ortho-Clinical Diagnostics, Inc.
- Current Assignee Address: US NJ Raritan
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/543 ; G01N33/566 ; C07K14/00
Abstract:
The aim of the present invention is to provide a non-intrusive way to isolate, concentrate and monitor the TSE disease-related pathogenic prion protein. The invention described several peptides and their ability to capture PrPSc from brain homogenate of prion disease infected animal and human. These eight peptides do not capture cellular prion protein from individual with no prion disease.
Public/Granted literature
- US20090136967A1 Peptides for Discrimination of Prions Public/Granted day:2009-05-28
Information query
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