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US07807407B2 Detection of truncation mutations by mass spectrometry 有权
通过质谱检测截短突变

Detection of truncation mutations by mass spectrometry
Abstract:
This invention relates to the detection and analysis by mass spec of nascent proteins, and in particular truncated proteins, translated within cellular or cell-free translation systems. N-terminal and C-terminal epitopes introduced into these nascent proteins permit rapid and efficient isolation, as well as a mass difference.
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