Invention Grant
- Patent Title: GAG binding protein
- Patent Title (中): GAG结合蛋白
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Application No.: US12131311Application Date: 2008-06-02
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Publication No.: US07807413B2Publication Date: 2010-10-05
- Inventor: Andreas J. Kungl
- Applicant: Andreas J. Kungl
- Applicant Address: AT Graz
- Assignee: Protaffin Biotechnologie AG
- Current Assignee: Protaffin Biotechnologie AG
- Current Assignee Address: AT Graz
- Agency: Perkins Coie LLP
- Priority: ATA1952/2003 20031204
- Main IPC: C12N15/63
- IPC: C12N15/63 ; C12N15/64 ; C12N5/10
Abstract:
A method is provided for introducing a GAG binding site into a protein comprising the steps: identifying a region in a protein which is not essential for structure maintenance introducing at least one basic amino acid into said site and/or deleting at least one bulky and/or acidic amino acid in said site, whereby said GAG binding site has a GAG binding affinity of Kd≦10 μM, preferably ≦1 μM, still preferred ≦0.1 μM, as well as modified GAG binding proteins.
Public/Granted literature
- US20090005541A1 GAG BINDING PROTEIN Public/Granted day:2009-01-01
Information query
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