Invention Grant
US07807424B2 Methods of producing polyketide synthase mutants and compositions and uses thereof
有权
生产聚酮化合物合酶突变体的方法及其组合物和用途
- Patent Title: Methods of producing polyketide synthase mutants and compositions and uses thereof
- Patent Title (中): 生产聚酮化合物合酶突变体的方法及其组合物和用途
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Application No.: US11876767Application Date: 2007-10-22
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Publication No.: US07807424B2Publication Date: 2010-10-05
- Inventor: Joseph P. Noel , Michael B. Austin , Marianne E. Bowman
- Applicant: Joseph P. Noel , Michael B. Austin , Marianne E. Bowman
- Applicant Address: US CA La Jolla
- Assignee: The Salk Institute for Biological Studies
- Current Assignee: The Salk Institute for Biological Studies
- Current Assignee Address: US CA La Jolla
- Agency: Foley & Lardner LLP
- Agent Stephen E. Reiter
- Main IPC: C12P7/00
- IPC: C12P7/00 ; C12N9/00
Abstract:
The present invention comprises crystalline polyketide synthases, isolated non-native polyketide synthases having the structural coordinates of said crystalline polyketide synthases, and nucleic acid encoding such non-native polyketide synthases. Also disclosed are methods of producing mutant polyketide synthases, and methods of altering the activity and/or substrate specificity of putative polyketide synthases.
Public/Granted literature
- US20090271888A1 METHODS OF PRODUCING POLYKETIDE SYNTHASE MUTANTS AND COMPOSITIONS AND USES THEREOF Public/Granted day:2009-10-29
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