The present disclosure generally relates to a high throughput system, apparatus, and methods useful for efficiently analyzing experimental liquid formulations applied to plants. In various embodiments, the high throughput system includes a liquid formulation dispensing subsystem (LFDS). The LFDS includes an automated moveable sample plate platform for holding at least one sample plate. Each sample plate includes a plurality of wells containing plant specimens. The LFDS is operable to sequentially position select ones of the wells at a well target location. Once a selected well is positioned at the target location, a micro-sprayer assembly, including at least one liquid formulation applicator, applies discrete amounts of a liquid formulation to the plant specimens within each selected well.