Invention Grant
US07807642B2 Tumor-associated peptides binding promiscuosly to human leukocyte antigen (HLA) class II molecules 有权
肿瘤相关肽预先结合人白细胞抗原(HLA)II类分子

Tumor-associated peptides binding promiscuosly to human leukocyte antigen (HLA) class II molecules
Abstract:
The present invention relates to immunotherapeutic methods, and molecules and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumour-associated T-helper cell peptide epitopes, alone or in combination with other tumour-associated peptides, that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumour immune responses. In particular, the present invention relates to 49 novel peptide sequences derived from HLA class II molecules of human tumour cell lines which can be used in vaccine compositions for eliciting anti-tumour immune responses.
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