Invention Grant
US07807667B2 1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl derivatives and their medical use
有权
1,4-二氮杂双环[3.2.2]壬基恶二唑基衍生物及其医疗用途
![1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl derivatives and their medical use](/docs/US/2010-10-05/US07807667B2/abs.jpg.600x600.jpg)
- Patent Title: 1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl derivatives and their medical use
- Patent Title (中): 1,4-二氮杂双环[3.2.2]壬基恶二唑基衍生物及其医疗用途
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Application No.: US12300060Application Date: 2007-05-29
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Publication No.: US07807667B2Publication Date: 2010-10-05
- Inventor: Dan Peters , Gunnar M. Olsen , Elsebet Østergaard Nielsen , Daniel B Timmermann , Steven Charles Loechel
- Applicant: Dan Peters , Gunnar M. Olsen , Elsebet Østergaard Nielsen , Daniel B Timmermann , Steven Charles Loechel
- Applicant Address: DK Ballerup
- Assignee: NeuroSearch A/S
- Current Assignee: NeuroSearch A/S
- Current Assignee Address: DK Ballerup
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: DK200600731 20060530
- International Application: PCT/EP2007/055169 WO 20070529
- International Announcement: WO2007/138038 WO 20071206
- Main IPC: A61P25/00
- IPC: A61P25/00 ; A61K31/551 ; C07D471/08
![1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl derivatives and their medical use](/abs-image/US/2010/10/05/US07807667B2/abs.jpg.150x150.jpg)
Abstract:
This invention relates to novel 1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl derivatives and their use in the manufacture of pharmaceutical compositions. The compounds of the invention are found to be cholinergic ligands at the nicotinic acetylcholine receptors.Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
Public/Granted literature
- US20090118266A1 NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONYL OXADIAZOLYL DERIVATIVES AND THEIR MEDICAL USE Public/Granted day:2009-05-07
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