Invention Grant
- Patent Title: Potent indole-3-carbinol-derived antitumor agents
- Patent Title (中): 强力吲哚-3-甲醇衍生的抗肿瘤剂
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Application No.: US12118591Application Date: 2008-05-09
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Publication No.: US07807705B2Publication Date: 2010-10-05
- Inventor: Ching-Shih Chen , Dasheng Wang , Jing-Ru Weng
- Applicant: Ching-Shih Chen , Dasheng Wang , Jing-Ru Weng
- Applicant Address: US OH Columbus
- Assignee: The Ohio State University Research Foundation
- Current Assignee: The Ohio State University Research Foundation
- Current Assignee Address: US OH Columbus
- Agency: Calfee, Halter & Griswold LLP
- Main IPC: A61K31/404
- IPC: A61K31/404 ; A61P35/00 ; C07D209/14

Abstract:
Compounds and methods for treating cancer and inducing apoptosis in unwanted rapidly proliferating cells. The compounds are shown in formula I: wherein X is hydroxyl or amino; Y is carboxyl or sulfonyl; R1, R2, R3, and R4 can be the same or different and are selected from hydrogen, halogen, methoxy, trifluoromethyl, hydroxyl and combinations thereof, R5, R6, and R7 may be the same or different and are selected from hydrogen, chloro, bromo, nitro, phenyl, amino, methoxy, and combinations thereof, and derivatives or metabolites thereof.
Public/Granted literature
- US20080300291A1 POTENT INDOLE-3-CARBINOL-DERIVED ANTITUMOR AGENTS Public/Granted day:2008-12-04
Information query
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