A device and method for canceling or attenuating harmonics noise without distorting the incoming signal. An exemplary device includes the use of an estimation loop to generate an artificial signal to eliminate or attenuate the influence of harmonics. The estimation loop includes a mixer adapted to produce a mixed signal by processing or combining the incoming signal and the artificial signal. The estimation loop includes an error detector, a low-pass filter, a parameter estimator, and a numerically controlled oscillator. The parameter estimator produces information relating to the phase, frequency, and amplitude of an incoming harmonics spur and will be used by the numerically controlled oscillator to generate the artificial signal. If the mixed signal contains relatively low levels of harmonics residuals, the mixed signal is produced at the output in lieu of the incoming signal.