A biosensor system determines an analyte concentration using one or more calibrated correlation equations for an optical and/or electrochemical analysis of a biological fluid. The biosensor system may be implemented using a measurement device and a sensor strip. The measurement device applies test signals to a sequential conductive pattern on a sensor strip. The measurement device selectively and sequentially connects test contacts with conductive and non-conductive areas on the sequential conductive pattern, which generates code signals in response to the test signals. The measurement device uses the code signals to calibrate one or more of the correlation equations. The measurement device uses the calibrated correlation equations to determine the analyte concentration.