An apparatus and method for controlling standby mode in an electronic device. In standby mode, power and clock signals are reduced or stopped to conserve power. The apparatus includes an initiator module coupled to a power and clock control module (PCCM). When the initiator module meets conditions for standby mode, the initiator module sends a standby signal to the PCCM and does not interact with other initiator, target, or interconnect modules. When the PCCM communicates a wait signal, the initiator module enters standby mode. When the initiator module detects a wakeup event, the standby signal is deactivated. In this state, the initiator module may process information but may not interact with other modules. When the PCCM deactivates the wait signal and returns power and clock signal to steady state levels, initiator module may resume normal operation.