Invention Grant
- Patent Title: Antibody-induced apoptosis
- Patent Title (中): 抗体诱导凋亡
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Application No.: US11981562Application Date: 2007-10-30
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Publication No.: US07811566B2Publication Date: 2010-10-12
- Inventor: Tsutomu Arakawa , Yoshiko Kita
- Applicant: Tsutomu Arakawa , Yoshiko Kita
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen, Inc.
- Current Assignee: Amgen, Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
Anti-Her2 antibodies which induce apoptosis in Her2 expressing cells are disclosed. The antibodies are used to “tag” Her2 overexpressing tumors for elimination by the host immune system. Also disclosed are hybridoma cell lines producing the antibodies, methods for treating cancer using the antibodies, and pharmaceutical compositions.
Public/Granted literature
- US20090142359A1 Antibody-induced apoptosis Public/Granted day:2009-06-04
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