Invention Grant
- Patent Title: Stable pharmaceutical composition of fluoroether compound for anesthetic use method for stabilizing a fluoroether compound, use of stabilizer agent for precluding the degradation of a fluoroether compound
- Patent Title (中): 用于稳定氟醚化合物的麻醉剂使用方法的氟醚化合物的稳定药物组合物，使用稳定剂来防止氟醚化合物的降解
-
Application No.: US10566466Application Date: 2004-08-20
-
Publication No.: US07816409B2Publication Date: 2010-10-19
- Inventor: Ogari Pacheco , Elisa Russo , Valter Russo , José Antônio Martins , Maria Alice Bockelmann , Simone Rosatto
- Applicant: Ogari Pacheco , Elisa Russo , Valter Russo , José Antônio Martins , Maria Alice Bockelmann , Simone Rosatto
- Applicant Address: BR Itapira, SP
- Assignee: Cristalia Productos Quimicos Farmaceuticos LTDA
- Current Assignee: Cristalia Productos Quimicos Farmaceuticos LTDA
- Current Assignee Address: BR Itapira, SP
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: BR0303489 20030910; BR07698 20040729
- International Application: PCT/BR2004/000156 WO 20040820
- International Announcement: WO2005/023175 WO 20050317
- Main IPC: A61K31/08
- IPC: A61K31/08 ; A01N31/14 ; C07C43/00
Abstract:
The present invention has as objective the stabilization of a fluoroether compound against degradation by acid substances. The stabilizers proposed are selected among propylene glycol, polyethylene glycol, hexylene glycol, 1,3-butylene glycol and a saturated cyclic alcohol preferably menthol and are used for preparing stable pharmaceutical compositions of a fluoroether compound. Method for stabilizing a fluoroether compound and use of stabilizers agents for precluding the degradation of a fluoroether are also described.
Public/Granted literature
Information query
