Invention Grant
US07816520B2 5,6-diphenyl-1,2,4-triazinic dimeric derivatives and the use thereof in the form of sun-protective agents
有权
5,6-二苯基-1,2,4-三嗪二聚体衍生物及其以防晒剂形式的用途
- Patent Title: 5,6-diphenyl-1,2,4-triazinic dimeric derivatives and the use thereof in the form of sun-protective agents
- Patent Title (中): 5,6-二苯基-1,2,4-三嗪二聚体衍生物及其以防晒剂形式的用途
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Application No.: US11579538Application Date: 2005-05-04
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Publication No.: US07816520B2Publication Date: 2010-10-19
- Inventor: Willy Picoul , Marco Ciufolini , Pascal Bordat , Roger Tarroux
- Applicant: Willy Picoul , Marco Ciufolini , Pascal Bordat , Roger Tarroux
- Applicant Address: FR Boulogne-Billancourt FR Paris FR Villeurbanne
- Assignee: Pierre Fabre Dermo-Cosmetique,Centre National de la Recherche Scientifique (CNRS),Universite Claude Bernard Lyon 1
- Current Assignee: Pierre Fabre Dermo-Cosmetique,Centre National de la Recherche Scientifique (CNRS),Universite Claude Bernard Lyon 1
- Current Assignee Address: FR Boulogne-Billancourt FR Paris FR Villeurbanne
- Agency: Birch, Stewart, Kolasch & Birch, LLP.
- Priority: FR0404811 20040505
- International Application: PCT/FR2005/001132 WO 20050504
- International Announcement: WO2005/121128 WO 20051222
- Main IPC: C07D403/10
- IPC: C07D403/10 ; C07D403/12 ; C07D403/14 ; A61K8/49 ; A61Q17/04

Abstract:
The invention relates to 5,6-diphenyl-1,2,4-triazinic compounds of general formula (I), wherein identical or different R1, R2, R3 and R4 represent a hydrogen, fluoride, chloride or bromine atom, C1 to C12 linear or branched alkyl, C1 A C18 linear or branched hydroxy, alkoxy poly(ethoxy)-alkoxy with a C1 to C4 alkyl fragment and an ethoxy number ranging from 1 to 4, amino or mono or di-alkylamino with a C1 to C4 alkyl fragment group, X is ortho-, meta- or paraphenylene, 4,4′-biphenylene, 2,4- or 2,6- or 3,4- or 3,5-pyridinylene, 2,2′-bipyridinylene, meta- or paraphenylenediamino, ethylenediamine, 2,2′-piperazinylene, diacyl of formula -(R4CO)2-, wherein r represents a phenyl radical, a 3 to 10 carbon, phenanthrene or anthracene atoms alkyl chain except 1,4-bis(5,6-diphenyl-1,2,4-triazin-3-yl)benzene of 2,4-bis(5,6-diphenyl-1,2,4-triazin-3-yl)pyridine and of 2,6-bis(5,6-diphenyl-1,2,4-triazin-3-yl)pyridine, to cosmetic compositions containing said compounds and to the use thereof in the form of sun filters or light-protective agents.
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