Invention Grant
- Patent Title: Glucagon receptor antagonists, preparation and therapeutic uses
- Patent Title (中): 胰高血糖素受体拮抗剂,制剂和治疗用途
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Application No.: US11570449Application Date: 2005-06-08
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Publication No.: US07816557B2Publication Date: 2010-10-19
- Inventor: Scott Eugene Conner , Guoxin Zhu
- Applicant: Scott Eugene Conner , Guoxin Zhu
- Applicant Address: US IN Indianapolis
- Assignee: Eli Lilly and Company
- Current Assignee: Eli Lilly and Company
- Current Assignee Address: US IN Indianapolis
- Agent Dan L. Wood
- International Application: PCT/US2005/019901 WO 20050608
- International Announcement: WO2005/123668 WO 20051229
- Main IPC: C07C323/60
- IPC: C07C323/60 ; C07C235/42 ; C07D213/62 ; A61K31/197

Abstract:
The present invention discloses novel compounds of Formula I, or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like.
Public/Granted literature
- US20070249688A1 Glucagon Receptor Antagonists, Preparation and Therapeutic Uses Public/Granted day:2007-10-25
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