Invention Grant
US07829076B2 Method of using interferon-like potein ZCYTO20 (IL-28A) or ZCYTO22(IL-28B) to treat hepatitis B
有权
使用干扰素样potein ZCYTO20（IL-28A）或ZCYTO22（IL-28B）治疗乙型肝炎的方法
- Patent Title: Method of using interferon-like potein ZCYTO20 (IL-28A) or ZCYTO22(IL-28B) to treat hepatitis B
- Patent Title (中): 使用干扰素样potein ZCYTO20（IL-28A）或ZCYTO22（IL-28B）治疗乙型肝炎的方法
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Application No.: US12630571Application Date: 2009-12-03
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Publication No.: US07829076B2Publication Date: 2010-11-09
- Inventor: Paul O. Sheppard , Brian A. Fox , Kevin M. Klucher , David W. Taft , Wayne Kindsvogel
- Applicant: Paul O. Sheppard , Brian A. Fox , Kevin M. Klucher , David W. Taft , Wayne Kindsvogel
- Applicant Address: US TN Nashville
- Assignee: ZymoGenetics, LLC
- Current Assignee: ZymoGenetics, LLC
- Current Assignee Address: US TN Nashville
- Agent Brian J. Walsh
- Main IPC: A61K38/20
- IPC: A61K38/20 ; A61K38/00 ; A61K38/21 ; C07K14/00
Abstract:
The present invention relates to polynucleotide and polypeptide molecules for zcyto20, zcyto21, zcyto22, zycto24, and zcyto25 proteins which are most closely related to interferon-α at the amino acid sequence level. The receptor for this protein family is a class II cytokine receptor. The present invention includes methods of reducing viral infections and increasing monocyte counts. The present invention also includes antibodies to the zcyto20 polypeptides, and methods of producing the polynucleotides and polypeptides.
Public/Granted literature
- US20100227813A1 A METHOD OF USING INTERFERON-LIKE POTEIN ZCYTO20 (IL-28A) OR ZCYTO22(IL-28B) TO TREAT HEPATITIS B Public/Granted day:2010-09-09
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