Invention Grant
US07829088B2 Composition comprising humanized antibody HBBK4 for the treatment of cancer and the use thereof
有权
包含用于治疗癌症的人源化抗体HBBK4的组合物及其用途
- Patent Title: Composition comprising humanized antibody HBBK4 for the treatment of cancer and the use thereof
- Patent Title (中): 包含用于治疗癌症的人源化抗体HBBK4的组合物及其用途
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Application No.: US11915371Application Date: 2006-05-24
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Publication No.: US07829088B2Publication Date: 2010-11-09
- Inventor: Byoung Se Kwon
- Applicant: Byoung Se Kwon
- Applicant Address: KR Ulsan
- Assignee: University of Ulsan Foundation for Industry Cooperation
- Current Assignee: University of Ulsan Foundation for Industry Cooperation
- Current Assignee Address: KR Ulsan
- Agency: Hogan Lovells US LLP
- Priority: KR10-2005-0043854 20050524
- International Application: PCT/KR2006/001963 WO 20060524
- International Announcement: WO2006/126835 WO 20061130
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/395 ; C07K16/00 ; C12P21/08
Abstract:
The present invention is related to a pharmaceutical composition comprising humanized anti-4-1BB antibody (HBBK4) for treating cancer by inducing increase of CD11+CD8+ T cell and IFN-γ, and inhibiting proliferation of cancer cells, together with a pharmaceutically acceptable carrier and the use. Accordingly, it can be useful in the prevention or treatment of cancer without adverse response.
Public/Granted literature
- US20090041763A1 Composition Comprising Humanized Antibody HBBK4 for the Treatment of Cancer and the Use Thereof Public/Granted day:2009-02-12
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