Invention Grant
- Patent Title: Inhibitory monoclonal antibody against blood clotting factor VII-activating protease
- Patent Title (中): 抗凝血因子Ⅶ活化蛋白酶的抑制性单克隆抗体
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Application No.: US10359704Application Date: 2003-02-07
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Publication No.: US07829095B2Publication Date: 2010-11-09
- Inventor: Juergen Roemisch , Wiegand Lang , Annette Feussner , Gudrun Muth-Naumann , Hans-Arnold Stoehr , Christian Kannemaier , Klaus Preissner , Fumie Nakazawa
- Applicant: Juergen Roemisch , Wiegand Lang , Annette Feussner , Gudrun Muth-Naumann , Hans-Arnold Stoehr , Christian Kannemaier , Klaus Preissner , Fumie Nakazawa
- Applicant Address: DE Marburg
- Assignee: CSL Behring GmbH
- Current Assignee: CSL Behring GmbH
- Current Assignee Address: DE Marburg
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Priority: DE10205520 20020208
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
A monoclonal antibody which inhibits the blood clotting factor VII-activating protease and its proenzyme and a blood clotting factor VII-activating protease, stabilized by the addition of said monoclonal antibody, and its proenzyme are described. A suitable monoclonal antibody is produced by hybridoma cell line DSM ACC 2533. The application of the inhibitory, monoclonal antibody in the stabilization of blood clotting preparations and in preparations for reducing the coagulability of the blood is disclosed.
Public/Granted literature
- US20030215447A1 Inhibitory monoclonal antibody against blood clotting factor VII-activating protease Public/Granted day:2003-11-20
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