Invention Grant
US07829104B2 Electroporation of Mycobacterium and overexpression of antigens in mycobacteria
有权
分枝杆菌的电穿孔和抗原在分枝杆菌中的过表达
- Patent Title: Electroporation of Mycobacterium and overexpression of antigens in mycobacteria
- Patent Title (中): 分枝杆菌的电穿孔和抗原在分枝杆菌中的过表达
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Application No.: US11755768Application Date: 2007-05-31
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Publication No.: US07829104B2Publication Date: 2010-11-09
- Inventor: Ronggai Sun , David Michael Hone , Jerald C. Sadoff
- Applicant: Ronggai Sun , David Michael Hone , Jerald C. Sadoff
- Applicant Address: US MD Bethesda
- Assignee: Aeras Global TB Vaccine Foundation
- Current Assignee: Aeras Global TB Vaccine Foundation
- Current Assignee Address: US MD Bethesda
- Agency: Whitham, Curtis, Christofferson & Cook, P.C.
- Main IPC: A61K39/04
- IPC: A61K39/04 ; A61K39/02 ; A61K39/12
Abstract:
Recombinant Mycobacterium strains with improved vaccinal properties for use as vaccinating agents are provided. The parent strains of the recombinant Mycobacterium strains are selected for their potent immunogenicity. The Mycobacterium strains do not display antibiotic resistance, and do not exhibit horizontal transfer to gram-negative bacteria.
Public/Granted literature
- US20080286852A1 Electroporation of Mycobacterium and Overexpression of Antigens in Mycobacteria Public/Granted day:2008-11-20
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