Invention Grant
- Patent Title: Catheter injectable depot compositions and uses thereof
- Patent Title (中): 导管可注射药剂组合物及其用途
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Application No.: US10295603Application Date: 2002-11-14
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Publication No.: US07829109B2Publication Date: 2010-11-09
- Inventor: Guohua Chen , Paul R. Houston , Lothar Kleiner , John Spaltro
- Applicant: Guohua Chen , Paul R. Houston , Lothar Kleiner , John Spaltro
- Applicant Address: US CA Cupertino
- Assignee: Durect Corporation
- Current Assignee: Durect Corporation
- Current Assignee Address: US CA Cupertino
- Agent Thomas P. McCracken
- Main IPC: A61F2/02
- IPC: A61F2/02

Abstract:
Catheter injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions have substantially improved shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection.
Public/Granted literature
- US20030180364A1 Catheter injectable depot compositions and uses thereof Public/Granted day:2003-09-25
Information query
IPC分类: