Invention Grant
- Patent Title: Method for determining the stage of ulcerative colitis or interstitial pneumonitis and reagent kit thereof
- Patent Title (中): 确定溃疡性结肠炎或间质性肺炎的阶段的方法及其试剂盒
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Application No.: US11910616Application Date: 2006-04-14
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Publication No.: US07829295B2Publication Date: 2010-11-09
- Inventor: Mutsunori Fujiwara , Isao Okayasu , Yuzo Hayashi
- Applicant: Mutsunori Fujiwara , Isao Okayasu , Yuzo Hayashi
- Applicant Address: JP Tokyo JP Sagamihara-shi JP Sagamihara-shi JP Tokyo
- Assignee: Mutsunori Fujiwara,Isao Okayasu,Yuzo Hayashi,Fujirebio Inc.
- Current Assignee: Mutsunori Fujiwara,Isao Okayasu,Yuzo Hayashi,Fujirebio Inc.
- Current Assignee Address: JP Tokyo JP Sagamihara-shi JP Sagamihara-shi JP Tokyo
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2005-117521 20050414
- International Application: PCT/JP2006/307939 WO 20060414
- International Announcement: WO2006/118004 WO 20061109
- Main IPC: G01N33/53
- IPC: G01N33/53

Abstract:
The invention provides a method capable of readily discriminating pathologic conditions and judging selection of a therapeutic drug, the degree of the therapeutic effect, discontinuation of medication, etc., wherein stages quantitatively judged by digitizing substances contained in urine, which is different from conventional methods for judging stages of an ulcerative colitis and an interstitial pneumonitis which are performed by observation of mucous lesions with endoscopy requiring the skill or by analysis of histological samples collected from the living body.The method measures the value of main metabolites of prostaglandin E (PGE-MUM) concentration in urine and judges stages between the pre-remission phase of and the remission phase of ulcerative colitis.The method also measures the value of the PGE-MUM concentration in urine and judges stages between the active phase and the non-active phase of interstitial pneumonitis.
Public/Granted literature
- US20090130775A1 METHOD FOR CLINICAL STAGING OF ULCERATIVE COLITIS OR INTERSTITIAL PNEUMONIA AND REAGENT KIT FOR THE SAME Public/Granted day:2009-05-21
Information query
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