Invention Grant
- Patent Title: Production of glucagon-like peptide 2
- Patent Title (中): 胰高血糖素样肽2的制备
-
Application No.: US10993127Application Date: 2004-11-22
-
Publication No.: US07829307B2Publication Date: 2010-11-09
- Inventor: Ken Sasaki , Vanessa Jane Williamson , Alberto de Araujo , Ewa Walczyk
- Applicant: Ken Sasaki , Vanessa Jane Williamson , Alberto de Araujo , Ewa Walczyk
- Applicant Address: US NJ Bedminster
- Assignee: NPS Pharmaceuticals, Inc.
- Current Assignee: NPS Pharmaceuticals, Inc.
- Current Assignee Address: US NJ Bedminster
- Agency: Stoel Rives LLP
- Main IPC: A61K38/28
- IPC: A61K38/28 ; A61K38/48 ; C12P21/06
Abstract:
GLP-2 peptides and analogs thereof are produced in high yield and with desired, authentic termini by isolation from a GLP-2 peptide multimer in which at least two units of GLP-2 peptide are coupled through a linker that presents an N-terminal acid cleavage site and a C-terminal enzyme cleavage site. In a specific embodiment, [Gly2]hGLP-2 is produced from a multimeric precursor comprising 2-30 units thereof.
Public/Granted literature
- US20050164930A1 Production of glucagon like peptide 2 and analogs Public/Granted day:2005-07-28
Information query
IPC分类:
