Invention Grant
- Patent Title: Substituted polyamines as inhibitors of bacterial efflux pumps
- Patent Title (中): 取代的多胺作为细菌外排泵的抑制剂
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Application No.: US10754041Application Date: 2004-01-07
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Publication No.: US07829543B2Publication Date: 2010-11-09
- Inventor: Mark L. Nelson , Michael N. Alekshun
- Applicant: Mark L. Nelson , Michael N. Alekshun
- Applicant Address: US MA Boston
- Assignee: Paratek Pharmaceuticals, Inc.
- Current Assignee: Paratek Pharmaceuticals, Inc.
- Current Assignee Address: US MA Boston
- Agency: McCarter & English, LLP
- Agent Elizabeth A. Hanley; Meaghan L. Richmond
- Main IPC: A61K31/7036
- IPC: A61K31/7036 ; A61K31/70 ; A61K31/715
Abstract:
Disclosed are methods of treating bacterial infections including those caused by multidrug resistant bacteria using polyamine efflux pump inhibiting compounds, including for example N-benzylated polyazaalkanes, N-benzylated polyaminoalkanes, or mixed N-benzylated poly(aza/amino)alkanes, optionally in combination with other drugs such as antibiotics, as well as pharmaceutical compositions thereof.
Public/Granted literature
- US20040204378A1 Substituted polyamines as inhibitors of bacterial efflux pumps Public/Granted day:2004-10-14
Information query
IPC分类:
