Invention Grant
- Patent Title: Aryl-substituted nitrogen-containing heterocyclic compounds
- Patent Title (中): 芳基取代的含氮杂环化合物
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Application No.: US11992817Application Date: 2006-09-28
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Publication No.: US07829586B2Publication Date: 2010-11-09
- Inventor: Hirokatsu Ito , Kensuke Kobayashi , Hisashi Ohta , Osamu Okamoto , Satoshi Ozaki , Tomohiro Tsujita
- Applicant: Hirokatsu Ito , Kensuke Kobayashi , Hisashi Ohta , Osamu Okamoto , Satoshi Ozaki , Tomohiro Tsujita
- Applicant Address: JP Kudankita, Chiyoda-ku, Tokyo
- Assignee: Banyu Pharmaceutical Co., Ltd.
- Current Assignee: Banyu Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Kudankita, Chiyoda-ku, Tokyo
- Agent J. Eric Thies; Gerard M. Devlin
- Priority: JP2005-288545 20050930
- International Application: PCT/JP2006/319912 WO 20060928
- International Announcement: WO2007/037513 WO 20070405
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; A61K31/415 ; A61K31/4184 ; C07D401/02 ; C07D235/02 ; C07D231/10

Abstract:
Disclosed is an aryl-substituted nitrogen-containing heterocyclic compound represented by the formula (I) below or a pharmaceutically acceptable salt thereof. This compound serves as nociceptin receptor antagonist and is useful as a pharmaceutical agent for treating diseases associated with a nociceptin receptor. (I) [in the formula, A1, A2 and A3 independently represent a carbon atom or a nitrogen atom, and one or two of A1, A2 and A3 represent a carbon atom; R1 represents a lower alkyl group or the like; R2 represents a phenyl group which may be substituted with a halogen atom or the like; R3 represents a hydrogen atom, a lower alkyl group or the like; and R4 represents a lower alkyl group or the like.]
Public/Granted literature
- US20090275617A1 Aryl-Substituted Nitrogen-Containing Heterocyclic Compounds Public/Granted day:2009-11-05
Information query
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