Invention Grant
US07829597B2 Benzylether and benzylamino beta-secretase inhibitors for the treatment of alzheimer's disease
有权
苄醚和苄氨基β-分泌酶抑制剂用于治疗阿尔茨海默病
- Patent Title: Benzylether and benzylamino beta-secretase inhibitors for the treatment of alzheimer's disease
- Patent Title (中): 苄醚和苄氨基β-分泌酶抑制剂用于治疗阿尔茨海默病
-
Application No.: US10573232Application Date: 2004-09-29
-
Publication No.: US07829597B2Publication Date: 2010-11-09
- Inventor: Philippe G. Nantermet , Hemaka Anthony Rajapakse , Harold G. Selnick
- Applicant: Philippe G. Nantermet , Hemaka Anthony Rajapakse , Harold G. Selnick
- Applicant Address: US NJ Rahway
- Assignee: Merck, Sharp & Dohme, Inc.
- Current Assignee: Merck, Sharp & Dohme, Inc.
- Current Assignee Address: US NJ Rahway
- Agent Keith D. MacMillan; John C. Todaro
- International Application: PCT/US2004/032009 WO 20040929
- International Announcement: WO2005/032471 WO 20050414
- Main IPC: C07C15/12
- IPC: C07C15/12 ; C07C13/48 ; A61K31/135
Abstract:
The present invention is directed to compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
Public/Granted literature
- US20060293380A1 Benzylether and benzylamino beta-secretase inhibitors for the treatment of alzheimer's disease Public/Granted day:2006-12-28
Information query
