Invention Grant
- Patent Title: Gene encoding a DNA repair enzyme and methods of use thereof
- Patent Title (中): 编码DNA修复酶的基因及其使用方法
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Application No.: US12354864Application Date: 2009-01-16
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Publication No.: US07829671B2Publication Date: 2010-11-09
- Inventor: Alfonso Bellacosa
- Applicant: Alfonso Bellacosa
- Applicant Address: US PA Philadelphia
- Assignee: Fox Chase Cancer Center
- Current Assignee: Fox Chase Cancer Center
- Current Assignee Address: US PA Philadelphia
- Agency: Dann, Dorfman, Herrell and Skillman, P.C.
- Agent Patrick J. Hagan
- Main IPC: C07K1/00
- IPC: C07K1/00 ; C07K14/00 ; C07K17/00 ; G01N33/00 ; G01N33/53 ; G01N33/573 ; A01N37/18 ; A01N61/00 ; A61K31/00 ; A61K38/00 ; A61K38/16 ; C12Q1/00
Abstract:
An isolated nucleic acid molecule encoding a human DNA repair enzyme, MED1, is disclosed. Like other mismatch repair genes which are mutated in certain cancers, MED1, encoding nucleic acids, proteins and antibodies thereto may be used to advantage in genetic or cancer screening assays. MED1, which recognizes and cleaves DNA, may also be used for the diagnostic detection of mutations and genetic variants.
Public/Granted literature
- US20090274681A1 NOVEL GENE ENCODING A DNA REPAIR ENZYME AND METHODS OF USE THEREOF Public/Granted day:2009-11-05
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