Invention Grant
- Patent Title: Nucleic acid encoding a subunit of Na+,K+-ATPase
- Patent Title (中): 编码Na +，K + -ATPase亚基的核酸
-
Application No.: US12626579Application Date: 2009-11-25
-
Publication No.: US07829686B2Publication Date: 2010-11-09
- Inventor: Alexandra Treschow , Sirac Dilber , Alar Aints
- Applicant: Alexandra Treschow , Sirac Dilber , Alar Aints
- Applicant Address: SE Huddinge
- Assignee: Avaris AB
- Current Assignee: Avaris AB
- Current Assignee Address: SE Huddinge
- Agency: Morrison & Foerster LLP
- Priority: SE0300412 20030214
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N9/00 ; C12N9/14 ; C12N1/20 ; C12N15/00
Abstract:
A recombinant Na+, K+-ATPase α1-subunit protein resistant to cardiac glycosides, e.g. oubain, is disclosed, as well as methods for its production and use. The resistance to cardiac glycosides are obtained by alterations in the region situated between and including the amino acids 65-133. Such recombinant protein and nucleic acid constructs expressing the same are useful as selection markers in gene therapy and research applications.
Public/Granted literature
- US20100081194A1 CELLS HAVING CARDIAC GLYCOSIDE RESISTANCE Public/Granted day:2010-04-01
Information query
